Michael,After adding the command to VOC this worked perfectly! Thanks!For anyone else having the issue this is what I ended up doing to make life easier:Made a new (really tiny) module:u2_numpy-- __init__.py-- u2_numpy.pyFile contents:__init__.py:from .u2_numpy import *u2_numpy.py:# I made some changes to u2py and have my own version. This line could be just import u2pyimport u2py_new as u2pycommand = u2py.Command("REINIT.PYTHON OFF")command.run()import numpyIn any module/file where I need to use numpy just do:import u2_numpy as numpyAnd you should be good to go! No issues for me as of yet.You would have to do this again if you wanted s different numpy type module (EX: Pandas). Potential way around this would be adding the u2py command to Numpy...but then you would have to "fix" it again on each package update.