The following error is displayed during Enterprise Server region Startup:

CASCD4007E Windows event logging error RC= 0000000005

This is a permissions issue. The user does not have necessary permissions to access the key and the RC=0005 is being returned as Access is denied.  You could run a ProcMon trace to track the access error in the registry and then use regedit to modify the settings.

The user you are logged in with needs to have "Full Control" and "Read" access to the registry key "HKLM\\SYSTEM\\CurrentControlSet\\Services\\Micro Focus Server\\Performance" .

If you go into regedit and look at the properties for the key, you will need to ensure the user is added with these permissions.