Problem:

Are Centrino Core 2 Duo processors that are 64-bit capable compatible with Net Express 5.0 64 bit?

Resolution:

According to:-

http://www.intel.com/products/centrino/duo/310199.pdf

the chip is compatible with X64.  This should be compatible with 64-bit applications created for X64 as long as they have a 64-bit operating system installed onto it.